منابع مشابه
Shutting Down the Thermohaline Circulation
Past climatic changes were caused by a slowdown of the thermohaline circulation. We use results from experiments with three climate models to show that the expected cooling due to a slowdown of the thermohaline circulation is less in magnitude than the expected warming due to increasing greenhouse gas concentrations. The integrated assessment model FUND and a meta-analysis of climate impacts ar...
متن کاملChromosomal deletions in bladder cancer: shutting down pathways.
Bladder cancer is one of the most common cancers in the world, leading to approximately 145,000 deaths annually. Bladder cancer is typically managed by surgical removal of the tumor; however, the recurrence rate is disappointingly very high, often requiring systemic chemotherapy. Improvement in the diagnosis and prognosis of bladder cancer will only come from a comprehensive understanding of th...
متن کاملNumerical investigations of the slow - down ofWhillans Ice Stream , West Antarctica : is it shutting down like Ice StreamC ?
We investigate whether the recent slow-down of Whillans Ice Stream (WIS),West Antarctica, may lead to its complete stoppage in the near future, using a numerical model. Basal resistance to ice-stream motion is represented by a continuous till layer whose strength changes in response to basal melting and freezing.We implement a basal drainage system, which acts to hinder ice-stream stoppage thro...
متن کامل(Near-Infra) Red Means STOP: Shutting Down Cancer with NIR Light
Killing cancer cells is easy. We have lots of ways to do it. For example, something as simple as a jar of formaldehyde stops respiring tissues in their tracks. Killing cancer cells while leaving the surrounding tissue intact is much harder. Despite decades of research, cancer treatment remains a therapeutic regime that often combats cancer at the expense of patient health. Because current cance...
متن کاملShutting down the power supply for DNA repair in cancer cells
Phosphoglycerate mutase 1 (PGAM1) functions in glycolysis. In this issue, Qu et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607008) show that PGAM1 inactivation leads to nucleotide depletion, which causes defective homologous recombination-mediated DNA repair, suggesting that targeting metabolic enzymes increases cancer cell susceptibility to DNA damaging agents.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Anthropology in Action
سال: 2020
ISSN: 0967-201X,1752-2285
DOI: 10.3167/aia.2020.270302